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Project INVEST

INVEST (INcreasing VaccinE uptake among Southern Teens) is a school-based program to reduce rural-urban disparities in HPV vaccination. This program was developed by researchers at the University of South Carolina and Duke University, with support from the Centers for Disease Control and Prevention, and can be customized to the needs of your school or school district. Project INVEST uses a multi-level approach with three key components:

  1. promotion of school nurses as trusted sources of information,

  2. dissemination of caregiver-targeted educational materials about adolescent wellness and vaccination, and

  3. linkage to vaccination providers in their local communities.

Customizable INVEST program materials

The customizable INVEST program materials contain the following materials:

Orientation packet

The orientation packet includes the orientation letter and sample vaccination resource list to introduce the INVEST program and link families to local vaccination providers in their community.

Follow-up vaccination infographic

The follow-up vaccination infographic lists information about all recommended adolescent vaccines.

Monthly Newsletters

The INVEST program includes six newsletters featuring adolescent health and wellness information including HPV vaccination information.


Newsletter topics are:

  • Healthy body

  • Healthy behaviors

  • Puberty

  • Navigating new social worlds

  • Mental health

  • Substance use


Click below to download the
customizable INVEST portfolio.

Social Media Content Calendar_edited.jpg

INVEST Social Media Content Calendar

The INVEST Social media content calendar contains sample messages and graphics for each month of the school year (August to May) to post on school or district social media accounts.


The calendar features messages about HPV vaccination (top row) and other adolescent vaccines or health topics (bottom row).


Most HPV-focused information has been adapted from Dr. Beth Sundstrom’s 'HPV Vaccination NOW: This is our Moment' social media campaign.

Click to download the social media content calendars in either          or         

Resources Library

The INVEST Resources Library lists many publicly available resources providing information about HPV and other adolescent vaccines, other adolescent health and wellness topics, and social media resources.


Additional publications from the Project INVEST team are listed for your reference. 


Vasudevan L, Ostermann J, Wang Y, Harrison SE, Yelverton V, McDonald JA, Fish LJ, Williams C, Walter EB. 

Vaccine. 2021 Dec 17;39(51):7485-7493.

Predictors of HPV vaccination in the southern US: A survey of caregivers from 13 states.


Harrison SE, Yelverton V, Wang Y, Ostermann J, Fish LJ, Williams CL, Vasudevan L, Walter EB.

Am J Health Behav. 2021 Sep 30;45(5):810-827.

Examining Associations between Knowledge and Vaccine Uptake Using the Human Papillomavirus Knowledge Questionnaire (HPV-KQ). 


Fish LJ, Harrison SE, McDonald JA, Yelverton V, Williams C, Walter EB, Vasudevan L. 

Hum Vaccin Immunother. 2022 Nov 30;18(5):2058264.

Key stakeholder perspectives on challenges and opportunities for rural HPV vaccination in North and South Carolina. 


Vasudevan L, Ostermann J, Wang Y, Harrison SE, Yelverton V, Fish LJ, Williams C, Walter EB.

Vaccine X. 2022 Jun 15;11:100181.

Association of caregiver attitudes with adolescent HPV vaccination in 13 southern states.

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